| Joanna Kramer in Kramer vs. Kramer |
| Karen Traynor in The Seduction of Joe Tynan |
| Sarah and Anna in The French Lieutenant's Woman |
| Sophie Zawistowski in Sophie's Choice |
| Brooke Reynolds in Still of the Night |
| Karen Silkwood in Silkwood |
| Molly Gilmore in Falling in Love |
| Karen in Out of Africa |
| Susan in Plenty |
| Rachel in Heartburn |
| Helen in Ironweed |
| Lindy in A Cry in the Dark |
| Mary Fisher in She-Devil |
| Suzanne Vale in Postcards from the Edge |
| Julia in Defending Your Life |
| Madeline Ashton Menville in Death Becomes Her |
| Clara in The House of the Spirits |
| Gail Hartman in The River Wild |
| Francesca Johnson in The Bridges of Madison County |
| Carolyn Ryan in Before and After |
| Lee in Marvin's Room |
| Kate Mundy in Dancing at Lughnasa |
| Kate Gulden in One True Thing |
| Roberta in Music of the Heart |
| Narrator in Eternal Memory: Voices from the Great Terror |
| Susan Orlean in Adaptation. |
| Clarissa Vaughan in The Hours |
| Aunt Josephine in A Series of Unfortunate Events |
| Eleanor Shaw in The Manchurian Candidate |
| Lisa Metzger in Prime |
| Joanna Silver in Dark Matter |
| Yolanda Johnson in A Prairie Home Companion |
| Queen in The Ant Bully |
| Mrs. Fox in Fantastic Mr. Fox |
| Chief Elder in The Giver |
| Miranda Priestly in The Devil Wears Prada |
| Donna in Mamma Mia! |
| Janine Roth in Lions for Lambs |
| Sister Aloysius Beauvier in Doubt |
| Margaret Thatcher in The Iron Lady |
| Dee Dee Allen in The Prom |
| Alice in Let Them All Talk |
| President Orlean in Don't Look Up |
| Julia Child in Julie & Julia |
| Narrator in Disneynature: Wings of Life |
| Jane Adler in It's Complicated |
| Violet Weston in August: Osage County |
| Narrator in Ocean Voyagers |
| Kay in Hope Springs |
| Narrator in A Fierce Green Fire: The Battle for A Living Planet |
| Narrator in Ginevra's Story: Solving the Mysteries of Leonardo da Vinci's First Known Portrait |
| Witch in Into the Woods |
| Emmeline Pankhurst in Suffragette |
| Ricki in Ricki and the Flash |
| Florence Foster Jenkins in Florence Foster Jenkins |
| Journals Performed by in Everybody Knows... Elizabeth Murray |
| Kay Graham in The Post |
| Donna in Mamma Mia! Here We Go Again |